While some mutants are interested in the "cure", including the X-Men's Rogue, many others are horrified by the announcement. Spoiler warning: Plot and/or ending details follow.Ī pharmaceutical company called Worthington Labs announces that it has developed an inoculation to suppress the X-gene that gives mutants their powers and makes them different from humans, offering the "cure" to any mutant who wants it. The film is sometimes colloquially referred to as X3 or X-Men 3. It is the highest-grossing of the series, earning over $458.7 million worldwide. Currently it holds the record for highest grossing movie during Memorial Day weekend totaling nearly $122.9 million in its first four days. Its opening-day gross of $45.5 million is the third-highest on record while its opening weekend gross of $102.75 million is the fifth highest ever. Despite mixed reviews from critics, the film has done extremely well at the box office. The film was released in the United States and Canada, and one or two days earlier in approximately 22 other countries. The film is based on two X-Men comic book story arcs: writer Chris Claremont's and artist John Byrne's " Dark Phoenix Saga" in The Uncanny X-Men (1980), and writer Joss Whedon's six-issue "Gifted" arc in Astonishing X-Men (2004). The movie revolves around a "mutant cure" that causes serious repercussions among mutants and humans, and on the mysterious resurrection of Jean Grey, who appeared to have died in X2. The previous two movies were X-Men (2000) and X2 (2003). It was directed by Brett Ratner and written by Simon Kinberg and Zak Penn. X-Men: The Last Stand is the third film adaptation of the Marvel Comics' X-Men superhero comic books. Related subjects: Films X-Men: The Last Stand
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